EHSTRAFD - Most Probable Geographical Origin
Release 2 (Projects:303; Populations: 451; STRs:100)

 

Description: MPGO is an EHSTRAFD module which allows searching for the Most Probable Geographical Origin of a given STR genetic profile. Geographical origin is estimated by the profile frequency in different populations. MPGO is available just for ISSOL, ESS and CODIS loci.
Instructions: • Populations are grouped in two main categories: "Labeled" - which refer to populations studied after a phenotypic, linguistic or other specific character (e.g. Caucasians, Berbers...) and do not reflect the entire population from a geographic area; and "Mixed" - which is the opposite of the first. You can choose one of them or both categories by selecting "All". • The number of STR loci can vary from 2 to 15 loci. For one locus we recommend AFGT Module. • Keep in mind that results depend on EHSTRAFD actual status, so before you start you should check if the locus status (chart from the right), the current release and/or populations status are convenient for your searches.		D2 Populations 85   TPOX Populations 284   D3 Populations 263   FGA Populations 274   D5 Populations 252   CSF Populations 270   D7 Populations 275   D8 Populations 245   TH01 Populations 319   vWA Populations 336   D13 Populations 272   D16 Populations 219   D18 Populations 253   D19 Populations 86   D21 Populations 238 EHSTRAFD Locus Status (move your mouse over the chart to highlight column details).

Populations:

All Labeled Mixed

1)

D2S1338

15 16 17 18 19 20 21 22 23 24 25 26 27 28

15 16 17 18 19 20 21 22 23 24 25 26 27 28

b

6)

CSF1PO

6 7 8 9 10 11 12 13 13_1 14 15 16 17 18

6 7 8 9 10 11 12 13 13_1 14 15 16 17 18

c

11)

D13S317

7 8 9 10 11 12 13 14 15

7 8 9 10 11 12 13 14 15

c

2)

TPOX

5 6 7 8 9 10 11 12 13

5 6 7 8 9 10 11 12 13

c

7)

D7S820

6 7 8 9 9_1 10 11 11_1 12 12_2 13 14 15

6 7 8 9 9_1 10 11 11_1 12 12_2 13 14 15

c

12)

D16S539

5 6 8 9 10 11 12 12_2 13 14 15 16

5 6 8 9 10 11 12 12_2 13 14 15 16

b,c

3)

D3S1358

6 7 9 11 12 13 14 15 16 17 18 19 20

6 7 9 11 12 13 14 15 16 17 18 19 20

a,b,c

8)

D8S1179

7 8 9 10 11 12 13 14 15 16 17 18

7 8 9 10 11 12 13 14 15 16 17 18

a,b,c

13)

D18S51

9 9_2 10 10_2 11 12 13 13_2 13_3 14 14_2 15 16 16_2 17 18 19 20 20_2 21 21_2 22 23 24 25 26

9 9_2 10 10_2 11 12 13 13_2 13_3 14 14_2 15 16 16_2 17 18 19 20 20_2 21 21_2 22 23 24 25 26

a,b,c

4)

FGA

10 16 17 18 18_1 19 20 20_2 21 21_2 22 22_2 23 23_2 24 24_2 25 25_2 26 26_2 27 28 29 30 30_2 31 31_2 41_1 43_1

10 16 17 18 18_1 19 20 20_2 21 21_2 22 22_2 23 23_2 24 24_2 25 25_2 26 26_2 27 28 29 30 30_2 31 31_2 41_1 43_1

a,b,c

9)

TH01

4 5 6 7 8 8_3 9 9_3 10 10_3 11 11_1 12 13 14

4 5 6 7 8 8_3 9 9_3 10 10_3 11 11_1 12 13 14

a,b,c

14)

D19S433

9 10 10_2 11 12 12_2 13 13_2 14 14_2 15 15_2 16 16_2 17 17_2 18 18_2 20

9 10 10_2 11 12 12_2 13 13_2 14 14_2 15 15_2 16 16_2 17 17_2 18 18_2 20

b

5)

D5S818

7 8 9 9_2 10 11 12 12_2 13 14 15 16 17

7 8 9 9_2 10 11 12 12_2 13 14 15 16 17

c

10)

VWA

11 12 13 14 15 15_2 16 17 18 18_1 19 20 20_2 21 22

11 12 13 14 15 15_2 16 17 18 18_1 19 20 20_2 21 22

a,b,c

15)

D21S11

23_2 24_2 25 25_2 26 27 27_2 28 28_2 29 29_2 30 30_2 31 31_2 32 32_2 33 33_1 33_2 34 34_1 34_2 35 35_2 36 38

23_2 24_2 25 25_2 26 27 27_2 28 28_2 29 29_2 30 30_2 31 31_2 32 32_2 33 33_1 33_2 34 34_1 34_2 35 35_2 36 38

a,b,c

a) ISSOL - Interpol Standard Set Of Loci; b) ESS - European Standard Set, recommended by ENFSI; c) CODIS - Combined DNA Index System.

Tips:
- Try several combinations of loci number (with few loci and many loci);
- Choose first those loci with a low mutation rate: TH01 (0.01), TPOX (0.01), D7S820 (0.1), D5S818 (0.11), D16S539 (0.11), D19S433 (0.11), D3S1358 (0.12), D2S1338 (0.12), D8S1179 (0.14), D13S317 (0.14), CSF1PO (0.16), VWA (0.17), D21S11 (0.19), D18S51 (0.22), FGA (0.28);
- Interpret your results base on the map locations - clustering criteria, and afterwards base on the genetic profile frequency table - sorting criteria.